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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
17.58
Human Site:
S424
Identified Species:
32.22
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S424
P
T
Q
R
V
S
C
S
C
S
R
H
K
L
L
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
D428
A
A
K
V
A
S
W
D
F
V
E
A
T
Q
R
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S424
P
T
Q
R
V
S
C
S
C
S
R
H
K
L
L
Dog
Lupus familis
XP_534693
2280
250152
S494
P
T
Q
R
V
S
C
S
C
S
R
H
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
S419
P
T
Q
R
V
S
C
S
C
S
R
H
K
L
L
Rat
Rattus norvegicus
NP_001101807
1374
149708
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
W409
T
A
D
K
V
A
S
W
D
F
V
E
A
T
Q
Chicken
Gallus gallus
XP_415317
2195
241321
S403
P
V
Q
R
V
S
C
S
C
S
R
H
K
V
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
Q373
I
P
R
R
L
A
S
Q
M
V
E
R
V
W
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
I563
P
M
Q
K
A
P
C
I
C
T
K
H
L
G
N
Honey Bee
Apis mellifera
XP_393643
1982
216109
I276
Y
P
I
N
S
S
N
I
E
A
G
L
P
P
L
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
L659
D
S
F
R
M
D
K
L
S
Q
D
D
W
A
N
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
6.6
80
N.A.
6.6
N.A.
33.3
13.3
6.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
0
N.A.
20
86.6
N.A.
26.6
N.A.
53.3
20
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
16
16
0
0
0
8
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
47
0
47
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
0
8
8
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
16
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
16
0
0
8
0
0
0
8
0
39
0
0
% K
% Leu:
0
0
0
0
8
0
0
8
0
0
0
8
8
31
39
% L
% Met:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
16
% N
% Pro:
47
16
0
0
0
8
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
47
0
0
0
0
8
0
8
0
0
0
8
16
% Q
% Arg:
0
0
8
54
0
0
0
0
0
0
39
8
0
0
8
% R
% Ser:
0
8
0
0
8
54
16
39
8
39
0
0
0
0
0
% S
% Thr:
8
31
0
0
0
0
0
0
0
8
0
0
8
8
0
% T
% Val:
0
8
0
8
47
0
0
0
0
16
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
0
8
8
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _